Prep HPLC Column, RP C4, 10um, 100A. 21.2mm ID x 100mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C4 Butyl is a reversed-phase HPLC stationary phase manufactured using high-purity silica with traditional butyl (C4) ligand bonding and complete double endcapping. The C4 chemistry provides moderate hydrophobic retention and is often selected when compounds are retained too strongly on C18 phases while requiring greater retention than a C8 phase. This stationary phase is widely used for purification of hydrophobic and neutral compounds and is particularly suitable for preparative HPLC applications involving small molecule isolation.
68004-P21-100 is a preparative HPLC column with dimensions of 21.2 mm ID x 100 mm length, packed with 10 µm RP C4 Butyl particles and a 100 Å pore size. The large internal diameter is designed for purification workflows where significantly greater sample loading is required compared to analytical columns. The 100 mm length provides a balance between throughput and chromatographic resolution, making it suitable for compound isolation, process development, and scale-up studies. Typical flow rates are approximately 15–40 mL/min depending on solvent conditions, system capabilities, and method requirements.
This column is intended for purification workflows where target compounds are collected for further research, development, formulation, or production. Applications include pharmaceutical and chemical research, natural product isolation, synthetic reaction cleanup, reference standard preparation, and pilot-scale purification. A preparative HPLC system capable of higher flow rates, larger injection volumes, and fraction collection is required. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
RP C4 Butyl stationary phase
Fully double endcapped chemistry
Traditional butyl (C4) bonded phase
Designed for preparative HPLC purification
High sample loading capacity
10 µm particles for lower operating backpressure
Suitable for higher flow rates
Less retention than C18 columns
Ideal for compound isolation and purification
Suitable for scale-up and process development
Typical Applications
Preparative HPLC purification
Small molecule isolation
Pharmaceutical research
Synthetic chemistry
Reaction cleanup
Reference standard preparation
Natural product purification
Process development
Pilot-scale purification
Fraction collection
Specifications
Product Type: Preparative HPLC Column
Stationary Phase: RP C4 Butyl
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 21.2 mm ID x 100 mm
Length: 100 mm
Typical Flow Rate: 15–40 mL/min
Brand: Cogent
Made‑to‑Order Columns & Pricing Information
Preparative and purification columns are manufactured to order and quoted based on current production requirements.
Special Order Item Information
Special Order Item Information
This item is a Special Order Item manufactured specifically to customer requirements.
Special Order Items cannot be canceled or returned once an order has been placed.
Manufactured upon receipt of order.
May have extended lead times compared to stocked products.
Important Notes
Designed for purification rather than routine analytical HPLC
Used to isolate and collect purified compounds
Offers substantially higher sample loading capacity than analytical columns
Requires a preparative HPLC system capable of higher flow rates and fraction collection
Less retentive than C18 phases while providing greater retention than many C8 columns
Suitable for research, process development, and production support applications
Special Order Item